- Reduced or absence of pancreatic exocrine secretion
- Cystic fbrosis
Adults: In the conditions with defcient pancreatic exocrine function such as-
- Following pancreatectomy
- Following total gastrectomy
- Chronic pancreatitis
- Celiac disease
Pancreatin is a preparation of Pancreatin having protease, lipase and amylase enzyme activity. Pancreatin hydrolyses fats to glycerol and fatty acids, changes protein into proteoses and derived substances and converts starch into dextrins and sugars. Pancreatin is employed in the conditions where the secretion of pancreatic juice is defcient.
1-3 tablets daily with meal or as per direction of the physician.
Alkaline media will rupture the enteric coating. As such to prevent bursting out of the content in the stomach Pancreatin should not be used concurrently with antacid.
Pancreatin may cause buccal and perianal soreness, particularly in infants. Hypersensitivity reactions have been reported; these may be sneezing, lacrimation or skin rashes.
Pregnancy category C. Not known whether Pancreatin is distributed into milk. Caution advised if Pancreatin is used.
A proper balance between fat, protein and starch intake must be maintained to avoid temporary indigestion.
Excessive dosage may produce a laxative efect. Systemic toxicity does not occur. Very high dosage may cause hyperuricemia and hyperuricos-uria.
Store in a cool and dry place. Keep out of the reach of children.