E-Cap Capsule 400 IU

৳ 6.50

Drug International Limited

Vitamin E (Alpha Tocopherol Acetate)

Indications

As a dietary supplement:

  • Vitamin E deficiency resulting from impaired absorption.
  • Increased requirements due to diet rich in polyunsaturated fats.
  • For healthy hair & skin
  • As an Antioxidant
  • Hemolytic anemia due to Vitamin E deficiency

Therapeutic use: Heavy metal poisoning, Hepatotoxin poisoning, Hemolytic anemia, Oxygen therapy and replacement therapy in nutritional deficiency states for the betterment of skin and hair.

Therapeutic Class

Vitamin-E Preparations

Pharmacology

Vitamin E Capsule is a Vitamin E preparation. Vitamin E acts as an antioxidant in the body. Vitamin E protects polyunsaturated fatty acids (which are components of cellular membrane) and other oxygen-sensitive substances such as vitamin A & vitamin C from oxidation. Vitamin E reacts with free radicals, which is the cause of oxidative damage to cell membranes, without the formation of another free radical in the process. The main pharmacological action of vitamin E in humans is its antioxidant effect.

In premature neonates irritability, edema, thrombosis and hemolytic anemia may be caused due to vitamin E deficiency. Creatinuria, ceroid deposition, muscle weakness, decreased erythrocyte survival or increased in vitro hemolysis by oxidizing agents have been identified in adults and children with low serum tocopherol concentrations.

Dosage & Administration

Betterment of Cardiovascular health: 400 mg – 800 mg / day

Deficiency syndrome in adults: 200 mg – 400 mg / day

Deficiency syndrome in children: 200 mg / day

Thalassemia: 800 mg / day

Sickle-cell anemia: 400 mg / day

Betterment of Skin & Hair: 200 mg – 400 mg / day (Topical use is also established for beautification)

Chronic cold in adults: 200 mg / day

Interaction

Vitamin E may impair the absorption of Vitamin A. Vitamin K functions impairement happens at the level of prothrombin formation and potentiates the effect of Warfarin.

Contraindications

No known contraindications found.

Side Effects

Overdoses (>1g) have been associated with minor side effects, including hypertension, fatigue, diarrhea and myopathy

Pregnancy & Lactation

Use in pregnancy: Vitamin E may be used in pregnancy in the normally recommended dose but the safety of high dose therapy has not been established.

Use in lactation: There appears to be no contraindication to breast feeding by mothers taking the normally recommended dose.

Precautions

Vitamin E may enhance the anticoagulant activity of anticoagulant drugs. Caution is advised in premature infants with high dose Vitamin E supplementation, because of reported risk of necrotizing enterocilitis.

Overdose Effects

Large doses of vitamin E (more than 1 gm/day) have been reported to increase bleeding tendency in vitamin K deficient patients such as those taking oral anticoagulants.

Use in Special Population

Use in Children: Vitamin E is safe for children

Storage Conditions

Store at a cool and dry place, Protect from light and moisture.

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