Pep-20 Tablet 20 mg

৳ 2.75

Orion Pharma Ltd.

Zinc Sulphate Monohydrate

Indications

Zinc Sulphate is indicated for Recurrent Respiratory Tract Infections; Diarrhoea; Loss of appetite; Severe growth retardation; Deformed bone formation; Impaired immunological response; Acrodermatitis enteropathica; Parakeratatic skin lesions; Defective and delayed wound healing; Anaemia; Night blindness; Mental disturbances

Therapeutic Class

Specific mineral preparations

Description

Zinc Sulfate Monohydrate is a source of Zinc which is an essential trace element and involved in a number of body enzyme systems. Symptoms of less severe Zinc deficiency include distorted or absent perceptions of taste and smell and poor wound healing. Severe Zinc deficiency causes skin lesion, alopecia, diarrhoea, increased susceptibility to infections and failure to thrive in children.

Pharmacology

Zinc is an essential trace mineral, which means that it must be obtained from the diet since the body cannot make enough. Next to iron, zinc is the most abundant trace mineral in the body. Stored primarily in muscle, zinc is also found in high concentrations in red and white blood cells, the retina of the eye, bones, skin, kidneys, liver, and pancreas. Some of the symptoms of zinc deficiency include loss of appetite, poor growth, weight loss, impaired taste or smell, poor wound healing, skin abnormalities (such as acne, atopic dermatitis and psoriasis), hair loss, night blindness, hypogonadism and delayed sexual maturation, white spots on the fingernails and feelings of depression.

Dosage

Syrup-

  • Children under 10 kg: One teaspoonful 2 times daily.
  • Children within 10 to 30 kg: Two teaspoonful 1-3 times daily.
  • Adults and children over 30 kg body weight: Four teaspoonful 1-3 times daily.

Tablet-
In the treatment of Diarrhoea Zinc should be given as soon as diarrhoea starts:

  • For infants between 2 to 6 months of age: 10 mg Zinc once daily for 10-14 days.
  • For children between 6 months to 5 years of age: 20 mg Zinc once daily for 10-14 days.

For other indications:

  • The recommended dose for children: 2 to 2.5 mg/kg/day.
  • Children under 10 kg: 10 mg Zinc 2 times daily.
  • Children within 10 to 30 kg: 20 mg Zinc 1-3 times daily.
  • Adults and children over 30 kg body weight: 40 mg Zinc 1-3 times daily.

Administration

Dispersible Tablet-

  • Place the tablet in a teaspoon
  • Add adequate amount of water
  • Let the tablet dissolve completely
  • Give the entire spoonful solution

Interaction

Zinc may inhibit the absorption of concurrently administered tetracyclines, when both are being given an interval of at least 3 hours.

Contraindications

It is contraindicated in patients with hypersensitivity to Zinc.

Side Effects

In case of zinc mild side effects such as gastric ulcer, nausea, vomiting, metallic taste, headache, drowsiness have been observed.

Pregnancy & Lactation

Pregnant women and nursing mothers should avoid zinc doses higher than RDA amounts.

Precautions

Concurrent administration of Zinc salt with penicillamine might diminish the effect of Penicillamine. The absorption of Zinc, although poor, may be decreased by various compounds including some foods. Chelation may occur with tetracyclines.

Overdose Effects

Zinc sulphate is corrosive in overdose. Symptoms are corrosion and inflammation of the mucous membrane of the mouth and stomach; ulceration of the stomach followed by perforation may occur. Gastric lavage and emesis should be avoided. Demulcents such as milk should be given. Chelating agents such as sodium edetate may be useful.

Storage Conditions

Store in a cool place. The syrup should be protected from light.

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